Inside Matthew Perry’s last days: The ‘Ketamine Queen’ and the ‘big one’ in a jacuzzi

On one occasion described in Iwamasa’s plea agreement, in mid-October, only a few weeks before the actors’s eventual death, Plasencia visited Perry’s home to inject him with ketamine — but something went wrong.

Perry’s blood pressure spiked and he froze up, unable to move or talk, according to prosecutors. Plasencia and Iwamasa helped move Perry to a couch until the effects wore off, according to the plea agreement.

“Let’s not do that again,” Plasencia said, before leaving, according to prosecutors.

The ‘Ketamine Queen’

Perry seemed to want more ketamine than what Plasencia could supply.

At around the same time as the incident where Perry froze up, Iwamasa reached out to Fleming.

“Hey Erik, Alfred here batmans butler He said I can text you directly,” Iwamasa told Fleming in a text message, as described in Iwamasa’s plea agreement. “How much do you want per bottle and what is the nice tip you want.”

Fleming texted Iwamasa an image of “a vial of ketamine with a horse image on the packaging,” as prosecutors described, and quoted $300 a vial. He asked for a $1,000 fee to deliver the goods.

Iwamasa said Perry would “probably want all the supply” but “not the horsey version.”

“only interested in the unmarked ones not the horsey version,” he wrote to Fleming. “Confirm with supply that the unmarked one is u.s. non veterinary supply or whatever they will tell you when you ask.”

In addition to its uses in treating humans, veterinarians use ketamine to tranquilize horses during surgery.

To get the vials of ketamine meant for human use, Fleming turned to Sangha — who prosecutors said was known to her customers as the “Ketamine Queen.”

“She only deal[s] with high end and celebs,” Fleming told Iwamasa in an encrypted text message. “If it were not great stuff she’d lose her business.”

At around the time law enforcement began investigating Perry’s death, Sangha was already in their sights.

In March, federal agents executed a search warrant at her home in North Hollywood. According to a DEA agent’s affidavit filed in court, they found methamphetamine, ketamine, MDMA, Xanax, psilocybin, and cocaine, as well as paraphernalia used to “cook” some of the drugs.

Prosecutors accused her of illegally possessing drugs with intent to distribute them. Sangha pleaded not guilty to the charges in May and was released on a $100,000 bond signed by her mother.

Chavez and lawyers for Iwamasa and Fleming didn’t immediately respond to requests for comment about their plea deals. The charges against Sangha and Plasencia were described in a superseding indictment brought by a grand jury on Wednesday.

According to Fleming’s plea agreement, Fleming brought Iwamasa a sample of Sangha’s ketamine on October 13.

Later that same day, Iwamasa told Fleming he’d buy “25 vials $5500 @220 +500 for you for logistics.”

Iwamasa rustled up $6,000 — including Fleming’s $500 cut. Fleming delivered the drugs to Iwamasa at Perry’s home the next day.

‘shoot me up with a big one’

On October 23, Iwamasa put in the same order with Fleming again.

Fleming delivered the drugs — and the four free lollipops — on October 24 at around 10:52 p.m.

Over the next few days — and at Perry’s direction — Iwamasa injected the “Friends” star with ketamine at least six times per day, according to Iwamasa’s plea agreement.

On October 28, Iwamasa was only able to inject Perry three times. He used syringes provided by Plasencia, according to the indictment against Plasencia and Sangha unsealed Thursday.

“shoot me up with a big one,” Perry told Iwamasa, telling him to prepare the third dose of the day and his jacuzzi, according to Iwamasa’s plea agreement.

Iwamasa left Perry’s home to take care of some errands. When he returned, he found Perry dead in his hot tub.

After news of Perry’s death became public, Sangha told Fleming to “Delete all our messages,” according to a screenshot of the texts included in the indictment against her.

Fleming agreed. According to the indictment, he later asked Sangha “Does K stay in your system or is it immediately flushed out.”

“I’m 90% sure everyone is protected,” Fleming said, according to prosecutors and before pleading guilty to charges in relation with Perry’s death.

Prosecutors say Plasencia also tried to cover his tracks. In response to a request to produce documents from his medical practice, he faked records that made it look like Perry was a legitimate patient, prosecutors said.

“Matthew Perry sought treatment for depression and anxiety and went to a local clinic where he became addicted to intravenous ketamine,” Anne Milgram, a DEA Administrator involved in investigating the case, said at a press conference Thursday. “When clinic doctors refused to increase his dosage, he turned to unscrupulous doctors who saw Perry as a way to make quick money.”

“Dr Placencia and Dr Chavez violated the oath they took to care for their patients,” she continued. “Instead of ‘do no harm,’ they did harm so that they could make more money.”

This story has been updated.